Document Type : Full paper (Original article)
Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
Department of Clinical Sciences, School of Veterinary Medicine, Kazeroon Branch, Islamic Azad University, Kazeroon, Iran
Department of Food Hygiene and Public Health, School of Veterinary Medicine, Shiraz University, Shiraz, Iran
This study was designed to evaluate serum and milk amyloid A (SAA) as an inflammatory indicator in inflammatory diseases. Twenty clinically healthy cows and 100 cows with various inflammatory diseases were selected for this study. Blood samples were collected from the coccygeal vein of both healthy and diseased groups. Milk samples were taken from four quarters of both groups. Milk samples of four quarters from each cow were mixed, then one sample was taken from pooled milk. There was significant difference in concentrations of serum and milk AA between clinically healthy cows and diseased cows (P<0.05). The difference of SAA and MAA between cows with subclinical mastitis and other inflammatory disease of cows was also significant (P<0.05). In conclusion, serum and milk amyloid A are useful diagnostic indicators in the inflammatory diseases of cows.