Document Type : Scientific report
Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran
Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Department of Parasitology, Faculty of Hygiene, University of Tehran, Tehran, Iran
Department of Food Hygiene and Public Health, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Ocular lesions are a common manifestation of toxoplasmosis in cats. In this survey, 10 healthy Syrian
mice were infected through intraperitoneal inoculation of bradyzoites of Toxoplasma gondii (Tehran strain).
Mice were killed 30 days after inoculation and the suspension of their brains was prepared, after confirmation
of the infection. Seven kittens were fed with the infected mice brain suspension. The kittens were 2.5–3
months old and had body weights of 650–900 g. All kittens shed oocyst 7–8 days after infection, and had
antibody titers as high as 1/320–1/1280 30 days after the challenge. Serum chemistry and complete blood
count were determined in all of the kittens. Examination of eyes was done with ophthalmoscope twice during
one week. Only one kitten showed unilateral anterior uveitis on day 16 after the infection was diagnosed
based on serology, oocyst shedding and other clinical signs.