Haemorrhagic septicaemia (HS) vaccine which is prepared in Razi Institute is used in endemic areas of Iran. Aluminum-hydroxide gel was used as adjuvant for preparing this vaccine. Post-vaccinal shock reactions were the main complaint after use of this vaccine. In a previous study, we could improve the vaccine by alum-precipitation Pasteurella multocida cells and removing the liquid phase. In this study, the amount of free endotoxin in aluminum-hydroxide and alum-HS vaccines was determined. It was found that endotoxin level was considerably decreased from 0.22 EU/ml to 0.03 EU/ml after alum-precipitation.
Jabbari, A. R., & Moazeni Jula, G. R. (2007). Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test. Iranian Journal of Veterinary Research, 8(1), 83-85. doi: 10.22099/ijvr.2007.2713
MLA
A. R. Jabbari; G. R. Moazeni Jula. "Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test", Iranian Journal of Veterinary Research, 8, 1, 2007, 83-85. doi: 10.22099/ijvr.2007.2713
HARVARD
Jabbari, A. R., Moazeni Jula, G. R. (2007). 'Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test', Iranian Journal of Veterinary Research, 8(1), pp. 83-85. doi: 10.22099/ijvr.2007.2713
VANCOUVER
Jabbari, A. R., Moazeni Jula, G. R. Measuring of free endotoxin in alum-precipitated vaccine of haemorrhagic septicaemia by limulus amebocyte lysate test. Iranian Journal of Veterinary Research, 2007; 8(1): 83-85. doi: 10.22099/ijvr.2007.2713
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