Diagnosis and management of hypoglycaemia due to pancreatic insulin-secreting neoplasia in a German shepherd dog

Document Type : Scientific report


1 Department of Clinical Sciences, Faculty of Veterinary Medicine, Karaj Branch, Islamic Azad University, Karaj, Iran

2 Department of Pathobiology, College of Veterinary Medicine, Lorestan University, Lorestan, Khorramabad, Iran

3 Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran. Tehran, Iran


A 7-year-old castrated male German shepherd dog was presented with a 10-day history of intermittent lethargy, weakness and episodic seizures. Laboratory findings after admission revealed hypoglycaemia and hyperinsulinaemia. Provisional diagnosis of insulinoma was made based on the presence of concurrent hypoglycaemia and elevated insulin level. In exploratory laparotomy a small nodular mass was detected on the pancreas. Other abdominal organs were normal in gross inspection. The mass was removed surgically. Histopathology of the excised pancreatic nodule confirmed the diagnosis of insulinoma. The dog became seizure free following the surgical operation.