The first report of clinical case of intestinal trichomoniasis caused by Tritrichomonas foetus in a cat with chronic diarrhea in Iran

Document Type : Scientific report

Authors

1 MSc Student in Internal Medicine, Department of Internal Medicine, Faculty of Veterinary Medicine, Islamic Azad University, Tehran, Iran

2 Resident of Clinical Pathology, Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

3 Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

10.22099/ijvr.2021.39422.5724

Abstract

Background: Tritrichomonas foetus is recently found to be one of the causes of chronic diarrhea in domestic cats but there is no report of feline intestinal trichomoniasis in Iran. Case description: A 9 months female domestic short-haired cat was referred to our hospital with a history of chronic diarrhea over the past two months, and with an unsuccessful previous antibiotic therapy in another clinic. Findings/treatment and outcome: Clinical examination revealed 39.8°C rectal temperature. Complete blood count (CBC) showed moderate inflammatory leukogram. By the wet-mount faecal assessment, moving organisms were observed. Rectal scarping dry-mount cytology revealed many inflammatory cells along with huge numbers of trophozoites with typical morphologic characteristics including central axostyle, undulating membrane, flagella, and one laterally located nucleus. Polymerase chain reaction (PCR) was performed and confirmed the diagnosis of T. foetus. After treatment with metronidazole and probiotics, the cat was completely recovered. Conclusion: This study represents the first case of intestinal trichomoniasis in a cat with chronic diarrhea in Iran.

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Crisi, PE; Paoletti, B; Morelli, S; Simonato, G; Colombo, M; Tiscar, G and Boari, A (2021). Tritrichomonas foetus in cats from Central Italy: Clinical signs and risk factors. Vet. Parasitol., 14: 100577.
Felleisen, RS (1999). Host-parasite interaction in bovine infection with Tritrichomonas foetus. Microbes Infect., 10: 807-816.
Foster, DM; Gookin, JL; Poore, MF; Stebbins, ME and Levy, MG (2004). Outcome of cats with diarrhea and Tritrichomonas foetus infection. J. Am. Vet. Med. Assoc., 225: 888-892.
Gookin, JL; Birkenheuer, AJ; Breitschwerdt, EB and Levy, MG (2002). Single-tube nested PCR for detection of Tritrichomonas foetus in feline feces. J. Clin. Microbiol., 40: 4126-4130.
Gookin, JL; Breitschwerdt, EB; Levy, MG; Gager, RB and Benrud, JG (1999). Diarrhea associated with trichomonosis in cats. J. Am. Vet. Med. Assoc., 215: 1450-1454.
Gookin, JL; Stauffer, SH; Coccaro, MR; Poore, MF; Levy, MG and Papich, MG (2007). Efficacy of tinidazole for treatment of cats experimentally infected with Tritrichomonas foetus. Am. J. Vet. Res., 68: 1085-1088.
Gookin, JL; Stebbins, ME; Hunt, E; Burlone, K; Fulton, M; Hochel, R; Talaat, M; Poore, M and Levy, MG (2004). Prevalence of and risk factors for feline Tritrichomonas foetus and giardia infection. J. Clin. Microbiol., 42: 2707-2710.
Levy, MG; Gookin, JL; Poore, M; Birkenheuer, AJ; Dykstra, MJ and Litaker, RW (2003). Tritrichomonas foetus and not Pentatrichomonas hominis is the etiologic agent of feline trichomonal diarrhea. J. Parasitol., 89: 99-104.
Lim, S; Park, SI; Ahn, KS; Oh, DS; Ryu, JS and Shin, SS (2010). First report of feline intestinal trichomoniasis caused by Tritrichomonas foetus in Korea. Korean J. Parasitol., 48: 247.
Manning, K (2010). Update on the diagnosis and management of Tritrichomonas foetus infections in cats. Top. Companion Anim. Med., 25: 145-148.
Tan, LP; Rani, MA; Sharma, RS; Syed Hussain, SS and Watanabe, M (2020). First molecular detection of Tritrichomonas foetus in domestic cats in Klang Valley, Malaysia. Trop. Biomed., 37: 756-762.
Tolbert, MK and Gookin, J (2009). Tritrichomonas foetus: a new agent of feline diarrhea. Compendium. 31: 374-381.
Tolbert, MK and Gookin, JL (2016). Mechanisms of Tritrichomonas foetus pathogenicity in cats with insights from venereal trichomonosis. J. Vet. Intern. Med., 30: 516-526.
Yaeger, MJ and Gookin, JL (2005). Histologic features associated with Tritrichomonas foetus-induced colitis in domestic cats. Vet. Parasitol., 42: 797-804.
Yao, C and Köster, LS (2015). Tritrichomonas foetus infection, a cause of chronic diarrhea in the domestic cat. Vet. Res., 46: 1-16.