TY - JOUR ID - 7004 TI - Primary type 3 abomasal ulceration in cattle and buffalo: clinico-biochemical parameters, treatment, and prognostic indicators JO - Iranian Journal of Veterinary Research JA - IJVR LA - en SN - 1728-1997 AU - Hussain, S. A. AU - Uppal, S. K. AU - Sood, N. K. AU - Mohindroo, J. AD - Division of Clinical Veterinary Medicine, Ethics and Jurisprudence, Faculty of Veterinary Sciences and Animal Husbandry, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Srinagar, Jammu and Kashmir-190006, India AD - Department of Veterinary Medicine, College of Veterinary Sciences, Guru Angad Dev Veterinary and Animal Sciences University (GADVASU), Ludhiana, Punjab 141004, India AD - Department of Teaching Veterinary Clinical Complex, College of Veterinary Sciences, Guru Angad Dev Veterinary and Animal Sciences University (GADVASU), Ludhiana, Punjab 141004, India AD - Department of Veterinary Surgery and Radiology, College of Veterinary Sciences, Guru Angad Dev Veterinary and Animal Sciences University (GADVASU), Ludhiana, Punjab 141004, India Y1 - 2023 PY - 2023 VL - 24 IS - 1 SP - 42 EP - 50 KW - Biochemistry KW - peritoneal fluid KW - Survival KW - therapy KW - type 3 abomasal ulcer DO - 10.22099/ijvr.2022.44324.6527 N2 - Background: The clinical findings, laboratory alterations, and prognosis of primary type 3 abomasal ulcer (AU3) are poorly reported in the literature. Aims: To describe clinical findings, hemato-biochemical changes, and peritoneal fluid changes in bovines suffering from primary AU3, and to monitor responses to medical treatment and outcomes. Methods: The study included 32 bovines (20 cattle and 12 buffaloes) diagnosed with primary AU3 along with a control group. Results: Common clinical findings were depressed demeanor, anorexia, dehydration, scanty feces, melena, mushy atonic rumen, tachycardia, and tachypnea. Colic was observed in 56.3% of animals. The mean hemoglobin, hematocrit, platelet count, and lymphocyte count were lower (P≤0.05), while WBC and neutrophil count were higher than the values of the control group (P≤0.05). The levels of BHBA, NEFA, glucose, total bilirubin, AST, CK, LDH, BUN, creatinine, and lactate were higher (P≤0.05), while cholesterol, total protein, albumin, sodium, potassium, chloride, and calcium were lower than the values of the control group (P≤0.05). The rumen chloride concentration was increased. The left shift was observed in a higher percentage of nonsurvivors than survivors (P≤0.05). The nonsurvivors had higher levels of bilirubin, CK, LDH, BUN, creatinine, and rumen chloride (P≤0.05), and lower levels of total protein, albumin, and globulin (P≤0.05). Conclusion: Type 3 abomasal ulcers occurred during the various stages of lactation as well as in pregnant animals. The response to medical treatment was fair, long time survival rate was good, and there was no recurrence. There was no effect on fetal survival or milk yield in the subsequent lactation. UR - https://ijvr.shirazu.ac.ir/article_7004.html L1 - https://ijvr.shirazu.ac.ir/article_7004_b1b1574029ff725afbeb9cc7f7f024ca.pdf ER -