TY - JOUR ID - 6905 TI - Vulvar and vestibulovaginal hemangiosarcoma in a cow: morphological and histopathological observations JO - Iranian Journal of Veterinary Research JA - IJVR LA - en SN - 1728-1997 AU - Stephan, F. AU - Sharun, K. AU - Varghese, E. AU - Hamza, P. AU - George, A. J. AD - 1MVSc Student in Livestock Production and Management, Livestock Production and Management Section, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India AD - Division of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India AD - MVSc Student in Veterinary Pathology, Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Pookode, Kerala Veterinary and Animal Sciences University, Wayanad, Kerala, India AD - Department of Veterinary Pathology, College of Veterinary and Animal Sciences, Pookode, Kerala Veterinary and Animal Sciences University, Wayanad, Kerala, India Y1 - 2022 PY - 2022 VL - 23 IS - 4 SP - 375 EP - 379 KW - Blood vascular tumor KW - Cattle KW - Hemangiosarcoma KW - Histopathology KW - Vaginal tumor DO - 10.22099/ijvr.2022.43412.6343 N2 - Background: Hemangiosarcoma is defined as the malignant mesenchymal neoplasm of endothelial cells. It is a common tumor affecting dogs and is very rare in cattle. Case description: A seven-year-old three months pregnant female Holstein Friesian cross-breed cow was presented with a history of a proliferating irregular dark red friable mass in the vulvar region for the past month. Findings/treatment and outcome: The surface of the mass had diffuse ecchymotic hemorrhages. Histopathological examination of the tissue biopsy specimen revealed unencapsulated, infiltrating neoplasm composed of numerous vascular channels with irregular borders surrounded by endothelial cells of variable sizes and shapes supported by a scanty fibrovascular stroma. Based on morphological and histopathological findings, the case was diagnosed as vulvar and vestibulovaginal hemangiosarcoma. The animal was culled due to the poor prognosis. Conclusion: To the best of our knowledge, this is the first report of vulvar and vestibulovaginal hemangiosarcoma in a cow. UR - https://ijvr.shirazu.ac.ir/article_6905.html L1 - https://ijvr.shirazu.ac.ir/article_6905_0d2e4d662edaad06a0e35f7b25f1975a.pdf ER -