%0 Journal Article %T Effect of systemic antibacterial administration during prepartum period on coagulase negative Staphylococcal intramammary infection in Holstein Heifers %J Iranian Journal of Veterinary Research %I Shiraz University %Z 1728-1997 %A Ataee, O. %A Hovareshti, P. %A Bolourchi, M. %A Barin, A. %A Gerami, A. %A Niasari-Naslaji, A. %D 2009 %\ 09/01/2009 %V 10 %N 3 %P 255-259 %! Effect of systemic antibacterial administration during prepartum period on coagulase negative Staphylococcal intramammary infection in Holstein Heifers %K Heifer mastitis %K Coagulase negative Staphylococcal %K Systemic antibacterial administration %R 10.22099/ijvr.2009.1701 %X A total of 183 coagulase negative Staphylococcal infected quarters and 64 uninfected quarters were randomly allotted to 4 experimental groups: infected quarters that did not receive any treatment (positive control group; n = 60); infected quarters that received Tylosin (n = 61) or Cefquinome (n = 62) and also uninfected quarters that did not receive any treatment were considered as negative control group (n = 64). Treated heifers received Tylosin or Cefquinome 10 to 14 days before the expected calving date. The bacteriological cure rate based on sampling obtained 3 days after calving was significantly higher (P<0.01) in mammary glands treated with systemic Tylosin (85.3%) than in the positive control group and mammary glands treated with systemic Cefquinome (69.4%). At the same time Tylosin treated heifers had significantly lower (P<0.01) somatic cell count scores compared to the positive control and Cefquinome groups. With the exception of one heifer that calved 8 days earlier than the expected calving date, there was no detectable antibiotic residues in the milk of the treated heifers on the 3rd day of lactation. %U https://ijvr.shirazu.ac.ir/article_1701_2328e51e0dcdf8a7abd9e21d4fdcd29e.pdf