1Department of Clinical Sciences, School of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran
2Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
A three-month-old male native puppy with lameness, metaphyseal swelling, pain, depression, inappetence and variable pyrexia was diagnosed as having hypertrophic osteodystrophy (HOD) based on radiologic examination. The hemogram and biochemical profiles were within normal limits. Radiologic examination revealed a radiolucent zone in the metaphyses and a radiopaque band near the physes of the appendicular long bones. Periosteal new bone formation was seen around of the distal metaphyses of the radii, ulnae and tibiae. Currently, there is no specific treatment for HOD. The condition of puppy was improved following restriction of activity, confinement to small well-padded area, administration of highquality diet and anti-inflammatory drug (aspirin, 10 mg/kg PO q12h for two weeks). To the best of our knowledge, it is the first report of HOD in mongrel puppies in Iran.