Mandibular primitive neuroectodermal tumor in an adult dog

Document Type: Scientific report

Authors

1 Department of Clinical Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

2 Department of Pathobiology, Science and Research Branch, Islamic Azad University, Tehran, Iran

3 DVM Student, Science and Research Branch, Islamic Azad University, Tehran, Iran

Abstract

This is the report of a mandibular neuroectodermal/ewing sarcoma in an 8-year-old male cross breed dog
that is unique because of tumor origin location. Pedunculated, ulcerative, firm 6.0 × 4.0 × 5.5 cm tumor mass
effaced the bone at the rostral part of the mandible and had a white-sanguineous color at cross section
appearance. Histopathologically, small round blue cell tumor was diagnosed. Immunohistochemically, tumor
cells were positive for vimentin, S100 and Glial fibrillary acidic protein (GFAP) and negative for neuron
specific enolase (NSE) and desmin. Mandibular location is a rare event in these types of tumors.

Keywords