Spontaneous differentiated squamous cell carcinoma of cheek pouch in a Syrian hamster

Document Type: Scientific report

Authors

1 Department of Clinical Sciences, Faculty of Veterinary Medicine, Karaj Branch, Islamic Azad University, Karaj, Iran

2 Department of Pathobiology, Faculty of Veterinary Medicine, Karaj Branch, Islamic Azad University, Karaj, Iran

3 Department of Pathobiology, College of Veterinary Medicine, Lorestan University, Lorestan, Khorramabad, Iran

Abstract

A 2-year-old male hamster was presented because of left facial swelling and salivation. Necropsy was
performed and affected cheek pouch with tissue samples of regional and internal organs were submitted for
histopathological study. In histopathological examination it was found that the tumor consisted of cords and
islands of tumoric epithelial cells which were diffused in the dermis. Vacoulation of cytoplasm in many cells
were striking features. The lesion was infiltrated by mononuclear cells. These findings were consistent with
differentiated squamous cell carcinoma, which restricted only to the left cheek pouch. There was no evidence
of tumoral invasion to the other organs. Cheek pouch spontaneous tumors in hamsters have been rarely
reported.

Keywords